Payer Policy Highlights

Cigna Expands GLP-1 Coverage & Removes Methadone Prior Authorization

Category: Payer Policy Digest | RCM Insights | Healthcare Coverage Updates

📅 Published: October 2025

Cigna Expands GLP-1 Coverage & Removes Methadone Prior Authorization (October 2025)

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Cigna Expands GLP-1 Coverage for Obesity, Cardiometabolic, and Sleep Apnea Care

Effective Date: October 2025

Payer: Cigna Healthcare

Policies Updated: IP0206, IP0621, IP0739

What Changed

Cigna has significantly expanded its GLP-1 therapy coverage for both adults and pediatric patients. The update broadens the use of Wegovy (semaglutide), Saxenda (liraglutide), and Zepbound (tirzepatide) beyond traditional obesity management, now encompassing cardiometabolic risk reduction and obstructive sleep apnea.

Policy Summary

  • Broader Eligibility: Coverage for adults with BMI ≥ 27 kg/m² plus at least one comorbidity (e.g., hypertension, T2DM, dyslipidemia).
  • Pediatric Inclusion: Saxenda approved for patients ≥ 60 kg meeting clinical obesity criteria.
  • Cardiovascular Indication: New coverage for obesity with established cardiovascular disease.
  • Obstructive Sleep Apnea (OSA): Added Zepbound for patients with moderate-to-severe OSA.
  • Extended Coverage Duration: Up to 1 year for pediatric use.
  • Titration Guidance: Pediatric Saxenda users may reduce to 2.4 mg daily if intolerant of 3 mg; escalation window extended to 8 weeks.
  • Clinical Documentation: Must include BMI reassessment after 12 weeks and chart documentation of comorbid conditions.
  • Concurrent Therapy: Clarified exclusion, cannot be combined with other FDA-approved weight-loss drugs.

Why It Matters for RCM Teams

  • Expect increased GLP-1 therapy claims under expanded ICD-10s for obesity, CVD, and OSA.
  • Denial prevention depends on accurate documentation of BMI, comorbidities, and progress at 12 weeks.
  • Prior authorization remains, but criteria are now clearer, improving predictability in approvals.

Reimbursement Impact

  • Potential higher claim volume for obesity and OSA-related care episodes.
  • Enhanced payment compliance via newly defined medical necessity language.
  • Anticipate payer audits for duplicate GLP-1 therapies in concurrent claim submissions.
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Cigna Removes Prior Authorization for Methadone in Opioid Use Disorder (OUD) Treatment

Effective Date: October 2025

Payer: Cigna Healthcare

Policy Updated: IP0561

What Changed

Cigna Healthcare has removed prior authorization requirements for Methadone used in Opioid Use Disorder (OUD) treatment within certified Opioid Treatment Programs (OTPs).

This policy streamlines access to methadone maintenance therapy and aligns with national goals to expand timely access to medication-assisted treatment (MAT) for opioid dependence.

Policy Summary

  • Prior Authorization: No longer required for methadone prescribed under approved OTPs.
  • Program Eligibility: Applies only to state-licensed, SAMHSA-certified treatment centers.
  • Documentation: Standard claim documentation (NPI, program certification) remains mandatory.
  • Other OUD Medications: Prior authorization for buprenorphine and naltrexone remains unchanged.
  • Reimbursement Scope: Applies to initial treatment and ongoing maintenance therapy.

Why It Matters for RCM Teams

  • Accelerates claims processing — reduces delays caused by PA review.
  • Improves patient retention in OUD programs, minimizing treatment gaps.
  • Decreases administrative burden for RCM teams managing addiction recovery billing.
  • May influence denial rates if documentation of certified OTP participation is missing.

Reimbursement Impact

  • Immediate eligibility for methadone maintenance billing under OTP codes.
  • Faster payment cycles and reduced rework in addiction treatment claims.
  • Encourages cross-functional coordination between behavioral health and medical billing teams.
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Summary: RCM Takeaways

Cigna's October 2025 updates reflect a decisive move toward access-driven coverage and policy simplification:

  • Broader GLP-1 coverage for obesity and cardiometabolic comorbidities.
  • Removal of Methadone prior authorization to enhance access to OUD care.
  • Clearer documentation and billing standards, helping RCM professionals optimize compliance.

Key Opportunities for RCM Teams:

  • Review GLP-1 claims templates to include BMI and comorbidity tracking fields.
  • Update EHR billing workflows to remove methadone PA flags under OTP claims.
  • Educate coding staff on policy IP0206, IP0621, IP0739, and IP0561 for accurate documentation.

Frequently Asked Questions

Cigna expanded GLP-1 coverage (policies IP0206, IP0621, IP0739) to include broader eligibility for adults and pediatric patients with obesity, cardiometabolic conditions, and obstructive sleep apnea (OSA). The update also extends coverage duration and clarifies dosing and documentation requirements.
Cigna's expanded policy includes Wegovy (semaglutide), Saxenda (liraglutide), and Zepbound (tirzepatide). Coverage applies when medical necessity and BMI/comorbidity documentation are provided.
No. Prior authorization for GLP-1 drugs remains in place, but criteria are now standardized and more transparent, improving approval predictability for RCM and clinical teams.
RCM teams should update documentation templates to include BMI, comorbidity evidence, and 12-week follow-up results. This ensures alignment with Cigna's new evidence-based coverage standards and minimizes claim denials.
As of October 2025 (policy IP0561), Cigna removed prior authorization for Methadone used within certified Opioid Treatment Programs (OTPs). This applies to both initial and maintenance therapy for opioid use disorder.
No. Coverage applies only to SAMHSA-certified and state-licensed OTPs. RCM teams must verify OTP certification details in claim submissions to avoid reimbursement denials.
It improves access to care and treatment continuity for individuals with opioid use disorder by eliminating administrative delays and supporting faster treatment initiation.
RCM teams should: • Remove prior authorization flags from OTP billing workflows. • Update claim templates to include OTP certification details. • Monitor payer updates for related opioid treatment medications (buprenorphine, naltrexone).
Both updates align with federal and payer-wide efforts to promote health equity, improve access to evidence-based obesity treatment, and reduce barriers to addiction recovery care.
Yes. Historically, Cigna's major policy shifts (like GLP-1 coverage expansion) are often followed by Aetna, Anthem, and UnitedHealthcare within the next 6–12 months, especially for access-related care initiatives.

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